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Moreover, the indole Main is substituted at R3 with a carbonyl team and that is also bonded to the napthalene moeity. Napthalene is usually a bicyclic composition of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it as a ketone. JWH-018 is surely an analog of THJ-018, by which the core indazole structure is substituted with the